Vitae

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General Information

Full Name Claudio Vinegoni
Affiliation Center for Systems Biology - MGH Harvard University
Contact cvinegoni [at] mgh [dot] harvard [dot] edu
Phone (+1)-857.891.4272
Languages Italian(mother tongue), English (fluent), German (colloquial), French, Arabic (elementary)

Current Position

  • Assistant Professor
    Center for Systems Biology at MGH-Harvard University

Research Areas

  • My research background is in physics focused in the optical imaging field. Specifically in fluorescence, fluorescence polarization and time resolved imaging techniques, multiphoton and confocal microscopy, Raman spectroscopy, Coherent anti-Stokes Raman Scattering (CARS) imaging, optical coherence microscopy and tomography, mesoscopic imaging, optical projection tomography, and fluorescence molecular tomography in diffusive regime for whole mouse imaging.
  • My current research focuses on cancer imaging, drug imaging, neural imaging and cardiovascular imaging.
  • Development of novel optical imaging platforms for motion compensation for in vivo heart imaging, molecular and label-free imaging, high throughput imaging systems for drug-target engagement, in vivo and in vitro studies of pharmacodynamics for fluorescently labeled drugs, longitudinal microscopy imaging study of insulitis in mice, development of optical imaging modalities for in vivo imaging.
  • Development of novel data acquisition (hardware and software), image processing and signal processing tools for motion compensation of physiological motion in living mice models.
  • Development of software tools for image data analysis and mining for quantification and classification in systems biology.
  • I also work on machine learning and AI methods applied in microscopy image processing to facilitate cellular segmentation and image resolution and contrast.

Education

  • 2001
    Universite de Geneve – Ph.D.
    Switzerland
  • 1998
    Universita di Trento – M.S. in Physics
    Italy
    • Tesi presentata alla Facolta di Scienze dell Universita di Trento
    • Advisor: Prof. Gino Mariotto and Enzo Cazzanelli Universita di Trento
    • Thesis: Structure and Vibrational Properties of Electrochromic Materials

Work Experience

  • 2011 - present
    Asst. Prof. at MGH-Harvard University - (Boston, USA)
    Center for Systems Biology
    • Development of a fluorescence based imaging system for for cardiovascular imaging.
    • In vivo drug imaging
    • Design of several fluorescence microscopy imaging platforms.
    • Machine learning and deep learning for data analysis and microscopy image processing.
  • 2008 - 2010
    Instructor of Radiology at MGH-Harvard University - (Boston, USA)
    Center for Systems Biology
    • Development of a fluorescence based imaging system for the detection of the vulnerable plaque in a clinical setting (catheter).
    • Design of several fluorescence microscopy imaging platforms.
  • 2005 - 2008
    Post-Doc researcher at MGH-Harvard University - (Boston, USA)
    Center for Molecular Imaging Research
    • Designed software for the reconstruction of whole body distribution of fluorescently labeled targeting agents in whole mouse.
    • Designed platform for molecular imaging photoacoustic tomography.
    • Design of imaging platform and computational software for in vivo mesoscopic tomographic imaging
  • 2003 - 2005
    Post-Doc researcher at the University of Illinois Urbana-Champaign - (USA)
    Biophotonics Imaging Laboratory
    • Development of optical imaging systems for molecular and structural biological characterization based on CARS and spectral-domain optical coherence tomography (OCT).
  • 2002 - 2003
    Guest research fellow at Chalmers University - (Goteborg, Sweden)
    Photonics Laboratory
    • Development of optical imaging systems for molecular and structural biological characterization based on CARS and spectral-domain optical coherence tomography (OCT).
  • 2001 - 2001
    Guest researcher at EXFO - (Quebec, CAN)
    Photonics R&D Center
    • Development of optical imaging systems for molecular and structural biological characterization based on CARS and spectral-domain optical coherence tomography (OCT).
  • 1998 - 1999
    Research fellow at University of Pittsuburgh- (PA, USA)
    Photonics Laboratory
    • Development of interferometric optical imaging system for label free imaging.
  • 1997 - 1998
    Technical Supervisor at the Univ. of Trento - (Trento, Italy)
    Laboratory of Ultrafast Spectroscopy
    • Development of optical imaging systems for molecular and structural biological characterization based on CARS and spectral-domain optical coherence tomography (OCT).
  • 1996 - 1997
    Technical Supervisor at the Univ. of Trento - (Trento, Italy)
    Raman Spectroscopy Laboratory
    • Development of optical imaging systems for molecular and structural biological characterization based on CARS and spectral-domain optical coherence tomography (OCT).

Scientific contributions

  • Author and coauthor of 183 scientific contributions. Among them, 3 Invited Review Chapters , 1 Patent , 111 articles published in peer-reviewed international scientific journals , 2 preprints , 35 oral presentations and poster sessions at international conferences, and 33 proceedings .

    Note: for further details on my research, please feel free to browse my full body of work page.

Bibliometrics Google

  • Citations: 10,473 on Google Scholar
    h-index: 47
    i10-index: 104
    Nr. Documents: 203

    Note: for further details please visit the bibliometrics page.

Bibliometrics Web of Science

  • Citations: 6,816 on Web of Science
    Citing Articles: 5,753 on Web of Science
    h-index: 39
    Nr. Documents: 112

    Note: for further details please visit the bibliometrics page.

Active contributions

  • Reviewer for the following journals: Advanced Science | Applied Physics Letters Photonics | Biomedical Optics Express | Biotechnology Journal | Circulation: Cardiovascular Imaging | Cytometry | eLife | Frontiers in Physics | Frontiers in Immunology | IEEE Access | IEEE Advances | IEEE Transactions on Information Technology in BioMedicine | IEEE Transaction on Biomedical Engineering | IEEE Transactions of Instrument. and Measurements | IEEE Transactions on Med. Imaging | IEEE Journal of Biomedical and Health Informatics | Int. J. of Biochemistry | Int. J. of Biomedical Imaging | JACC: Cardiovascular Imaging | Journal of Biophotonics | J. Lightwave Technology | Journal of Mathematical Imaging and Vision | Journal of Microscopy | Journal of Molecular Imaging | Journal Nuclear Medicine | JOVE | Methods and Applications in Fluorescence | Micromachines | Molecular Imaging | Molecular Imaging and Biology | Nature Communications | Nature Methods | Nature Protocols | Optica | Optics Communications | Optics Express | Optics Letters | Photoacoustics | Photonics and Technology Letters | PhotoniX | Physical Review A | Physical Review E | PlosOne | Review of Scientific Instruments | Scientific Reports | SLAS Discovery.
  • Chair of the ”Molecular Infrared and other novel imaging modalities” session at IEEE Engineering Medicine and Biology, Boston USA (2011).
  • Technical Program Committee of the IEEE Biomedical and Health Informatics, Hong Kong (2012).
  • Associate Editor, Biomedical Imaging and Image Processing, IEEE Engineering Medicine and Biology (2012-2023)
  • Editorial Board ”Scientific Reports” in the category Electronics, Photonics and Device Physics
  • Associate Editor ”Frontiers in Physics” in the category Medical Physics and Imaging