Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles

Optics Letters

  1. Opt. Lett.
    Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles
    Vinegoni#†, C., Razansky†, D., Hilderbrand, S. A., Shao, F. W., Ntziachristos, V., and Weissleder, R.
    Optics Letters 2009
    ABS URL PMID DOI PMCID CITE HTML PDF

Abstract

"We report on a systematic study of upconverting fluorescence signal generation within turbid phantoms and real tissues. An accurate three-point Green's function, describing the forward model of photon propagation, is established and experimentally validated. We further demonstrate, for the first time to our knowledge, autofluorescence-free transillumination imaging of mice that have received biocompatible upconverting nanoparticles. The method holds great promise for artifact-free whole-body visualization of optical molecular probes. (C) 2009 Optical Society of America"

Full citation

For attribution in academic contexts, please cite this work as:
Vinegoni#†, C., Razansky†, D., Hilderbrand, S. A., Shao, F. W., Ntziachristos, V., & Weissleder, R. (2009). Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles. Optics Letters, 34(17), 2566–2568. https://doi.org/10.1364/ol.34.002566



Vinegoni#†, C., Razansky†, D., Hilderbrand, S. A., Shao, F. W., Ntziachristos, V., & Weissleder, R. (2009). Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles. Optics Letters, 34(17), 2566–2568. https://doi.org/10.1364/ol.34.002566