We present a normalized Born approach for fluorescence optical projection tomography that takes into account tissue absorption properties. This approach can be particularly useful to study fluorochrome distribution within tissue. We use the algorithm to three-dimensionally reconstruct and characterize a fluorescein isothiocyanate containing absorptive phantom and an infarcted mouse heart previously injected with a fluorescent molecular probe. (C) 2009 Optical Society of America
19183644
PMC2771918
10.1364/ol.34.000319
Abstract
"We present a normalized Born approach for fluorescence optical projection tomography that takes into account tissue absorption properties. This approach can be particularly useful to study fluorochrome distribution within tissue. We use the algorithm to three-dimensionally reconstruct and characterize a fluorescein isothiocyanate containing absorptive phantom and an infarcted mouse heart previously injected with a fluorescent molecular probe. (C) 2009 Optical Society of America"
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For attribution in academic contexts, please cite this work as:
Vinegoni#, C., Razansky, D., Figueiredo, J. L., Nahrendorf, M., Ntziachristos, V., & Weissleder, R. (2009). Normalized Born ratio for fluorescence optical projection tomography. Optics Letters, 34(3), 319–321. https://doi.org/10.1364/ol.34.000319
Vinegoni#, C., Razansky, D., Figueiredo, J. L., Nahrendorf, M., Ntziachristos, V., & Weissleder, R. (2009). Normalized Born ratio for fluorescence optical projection tomography. Optics Letters, 34(3), 319–321. https://doi.org/10.1364/ol.34.000319