Measuring key pharmacokinetic and pharmacodynamic parameters in vivo at the single cell level is likely to enhance drug discovery and development. In this review, we summarize recent advances in this field and highlight current and future capabilities.
26024776
PMC4567932
10.1016/j.drudis.2015.05.011
Abstract
"Measuring key pharmacokinetic and pharmacodynamic parameters in vivo at the single cell level is likely to enhance drug discovery and development. In this review, we summarize recent advances in this field and highlight current and future capabilities."
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Vinegoni#, C., Dubach, J. M., Thurber, G. M., Miller, M. A., Mazitschek, R., & Weissleder, R. (2015). Advances in measuring single-cell pharmacology in vivo. Drug Discovery Today, 20(9), 1087–1092. https://doi.org/10.1016/j.drudis.2015.05.011
Vinegoni#, C., Dubach, J. M., Thurber, G. M., Miller, M. A., Mazitschek, R., & Weissleder, R. (2015). Advances in measuring single-cell pharmacology in vivo. Drug Discovery Today, 20(9), 1087–1092. https://doi.org/10.1016/j.drudis.2015.05.011